CUSTODIOL®-CE HTK BRETSCHNEIDER®
Hair Transplantation & Graft Preservation Solutions
The superior graft preservation technology that carries its proven success in organ transplantation and cardiovascular surgery into hair transplantation procedures.
One of the most important factors determining the success of hair transplantation procedures is the ability of follicular units harvested from the donor area to maintain their viability throughout the period until implantation. In modern hair transplantation, graft preservation and storage play as critical a role in the final outcome of the procedure as the surgical techniques themselves.
Hair follicles extracted from the donor area are deprived of oxygen, nutrients and energy sources from the moment they are separated from natural blood circulation. Cellular stress, dehydration, hypoxia, ATP loss and free radical damage that may occur during this period can directly affect graft quality and post-transplantation survival rates.
CUSTODIOL®-CE HTK BRETSCHNEIDER® is an internationally recognized hypothermic preservation solution that has been used in organ, tissue and cell preservation for decades. It now carries its success in organ transplantation and cardiovascular surgery into graft preservation processes in hair transplantation procedures.
FOLLICULAR UNITS
Why Must Grafts Be Preserved?
During hair transplantation, follicular units are separated from blood circulation and lose their natural support systems. Without adequate preservation, graft viability may decrease and post-transplantation growth performance may be adversely affected. For this reason, preserving grafts at controlled temperatures in specialized preservation solutions is of great importance in modern hair transplantation centers.
Risks Threatening Graft Viability
- Separation from blood circulation
- Loss of oxygen supply
- Decreased cellular energy production
- Risk of dehydration
- Free radical formation
- Ischemia and reperfusion injury
FORMULATION
How Does CUSTODIOL® HTK Work?
Histidine / Histidine-HCl Buffer SystemThanks to its high-concentration Histidine content, it provides strong buffering capacity. This property helps reduce metabolic acidosis that may occur in cells and supports the maintenance of intracellular pH balance.
TryptophanHelps protect follicular cell membranes and supports the maintenance of cellular integrity.
α-KetoglutarateAn important component involved in cellular energy metabolism. Contributes to meeting the energy needs of cells by supporting ATP production.
MannitolThanks to its antioxidant properties, helps reduce the effects of free radicals while providing protective support against cellular edema formation.
COMPARISON
How It Differs from Traditional Saline Solutions
Many hair transplantation centers use sterile saline solutions for graft preservation. While saline solutions keep grafts moist, they have limited properties in terms of cellular protection and metabolic support.
Salin Solüsyonu
- ✗Provides moisture only
- ✗Cellular protection is limited
- ✗Offers no metabolic support
- ✗No antioxidant properties
- ✗pH balance cannot be maintained
CUSTODIOL® HTK
- ✓Provides cellular protection
- ✓ Offers antioxidant support
- ✓Maintains pH balance
- ✓Supports cell membranes
- ✓Creates a hypothermic preservation environment
IN HAIR TRANSPLANTATION
Advantages It Provides
01
Preservation of Graft Viability
Helps maintain the viability of follicular units throughout the period they remain outside the body.
02
Reduction of Cellular Stress
Supports the reduction of cellular stress that may occur during cooling and rewarming processes.
03
Antioxidant Protection
Contains components that provide a protective effect against free radical formation.
04
Controlled Hypothermic Storage
Helps slow metabolic activity with hypothermic preservation applied between +2°C and +8°C.
05
Ready-to-Use Formulation
Can be used directly without any additional additives or filtration.
WHY US?
Why Dr. Köhler Medikal?
Dr. Köhler Medikal brings its expertise in organ transplantation, tissue preservation and medical technologies to the hair transplantation sector, providing clinics with reliable graft preservation solutions.
- ✓Original CUSTODIOL® HTK — Made in Germany
- ✓CE certified and manufactured in compliance with international quality standards
- ✓Decades of clinical experience in organ and tissue preservation
- ✓Nationwide sales and technical support network across Türkiye
- ✓Specialized training and product support for hair transplantation centers
A successful hair transplantation procedure is only possible not just with the right surgical technique, but also with grafts being preserved under optimal conditions throughout the procedure.
CUSTODIOL®-CE HTK BRETSCHNEIDER® brings its scientific expertise in organ and tissue preservation to hair transplantation procedures, offering a reliable and innovative solution in graft preservation processes.