ORIGINAL HTK SOLUTION
CUSTODIOL®-CE HTK BRETSCHNEIDER®
CUSTODIOL is the original HTK solution trusted in millions of procedures worldwide across organ transplantation, cardiovascular surgery, tissue preservation and hair transplantation.
CUSTODIOL®-CE HTK BRETSCHNEIDER® is the original Histidine–Tryptophan–Ketoglutarate (HTK) solution developed by Prof. Hans J. Bretschneider and
Dr. Franz J. Köhler, used worldwide in organ transplantation and cardiovascular surgery.
Initially developed as a cardioplegic solution, CUSTODIOL® HTK has become one of the most widely preferred solutions for the preservation and transplantation of organs such as the heart, kidney, liver and pancreas. Used in more than 90 countries, the product has been successfully applied in millions of surgical and transplantation procedures.
AREAS OF APPLICATION
Preferred Areas of Use
A scientifically based graft preservation solution for maintaining follicular unit viability throughout the procedure.
All Areas of Use
- — Cardiac Surgery and Cardioplegia
- —Heart Transplantation
- — Kidney Transplantation
- —Liver Transplantation
- — Pancreas Transplantation
- — Multi-Organ Transplantation
- — Donor Organ Preservation and Transportation
- — Minimally Invasive Cardiac Surgery
- — Pediatric Cardiac Surgery
- — Coronary Artery Bypass Surgery (CABG)
- — Aortic Surgery
- — Endothelium-Focused Cardiovascular Applications
- — Tissue and Graft Preservation
- — Graft Preservation and Storage in Hair Transplantation Procedures
- — Regenerative Medicine and Cell Preservation Studies
WHY CUSTODIOL®
Key Advantages
Single-Dose ApplicationA single application provides myocardial protection for up to 180 minutes, reducing the need for repeated cardioplegia during surgery.
High Buffering CapacityThe Histidine/Histidine-HCl system provides strong protection against acidosis that may occur during ischemia.
Endothelial and Myocardial ProtectionProvides protective effects not only on cardiac tissue but also on vascular endothelium, supporting post-operative recovery.
Low ViscosityIts low viscosity allows for rapid and effective perfusion of organs.
Ready to UseReady for direct use without any filtration or additional additives.
Clinically Proven ReliabilitySupported by more than 900 scientific publications and decades of clinical experience.
FORMULATION
Technical Specifications
CUSTODIOL® HTK
Why CUSTODIOL® HTK?
- ✓Long-term protection with single-dose application
- ✓High buffering capacity
- ✓Endothelial and myocardial protection
- ✓Effective perfusion with low viscosity
- ✓Ready-to-use formulation
- ✓Millions of successful applications worldwide
- ✓Proven reliability in organ transplantation and cardiovascular surgery
- ✓One of the preferred preservation solutions in hair transplantation and graft protection
CUSTODIOL®-CE HTK BRETSCHNEIDER® is the original HTK solution internationally recognized in organ transplantation and cardiac surgery, suitable for the preservation of both abdominal and thoracic organs. Its reliable formulation, extended preservation duration and clinically proven performance make it the preferred choice of transplantation centers and cardiac surgery teams worldwide.
As Dr. Köhler Medikal, we provide sales, distribution and technical support services for CUSTODIOL®-CE HTK BRETSCHNEIDER® in
Türkiye, Azerbaijan, Kyrgyzstan and Tajikistan with our expert team.